Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Fluoro-5-formylbenzonitrile

  • CAS No. 1003708-42-6

  • Cat. No. CS-W018980
  • Purity≥98%
  • MDL No.MFCD04974123

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-formylbenzonitrile|CS-W018980

Structure of 1003708-42-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1003708-42-6
  • Cat. No. CS-W018980
  • Purity ≥98%
  • MDL No. MFCD04974123
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄FNO
  • Molecular Weight 149.12
  • Synonym(s) 3-cyano-5-fluorobenzaldehyde
  • SMILES FC1=CC(=CC(=C1)C#N)C=O

Description

3-Fluoro-5-formylbenzonitrile features a strategically positioned formyl group flanked by fluorine and cyano substituents, enabling direct integration into heterocyclic scaffolds. This electron-deficient aromatic core facilitates coupling reactions under mild conditions and serves as a key intermediate in the synthesis of bioactive molecules.

Application

3-Fluoro-5-formylbenzonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of substituted heterocycles and functionalized aromatic scaffolds. The ortho-fluoro and formyl groups facilitate directed metallation and electrophilic substitution, while the nitrile group offers compatibility with nucleophilic additions and cyclizations. Its bench-stable nature and predictable reactivity streamline purification and integration into multi-step syntheses.

Synthesis

  • Route1
    • null|null
      68-12-2
    • In-stock
      3-Bromo-5-fluorobenzonitrile|CS-D1719
      179898-34-1
    • ~10%
    • In-stock
      3-Fluoro-5-formylbenzonitrile|CS-W018980
      1003708-42-6

    References

    • ARRAY BIOPHARMA INC.; ALLEN, Shelley; ANDREWS, Steven Wade; BLAKE, James F.; BRANDHUBER, Barbara J.; JIANG, Yutong; KERCHER, Timothy; WINSKI, Shannon L. Patent: WO2014/78372 A1, 2014 ; Location in patent: Paragraph 00375 ;
  • Route2
    • In-stock
      3-Cyanobenzaldehyde|CS-W007808
      24964-64-5
    • ~23%
    • In-stock
      3-Fluoro-5-formylbenzonitrile|CS-W018980
      1003708-42-6
    • null|null
      77976-07-9

    References

    • Chambers, Richard D.; Sandford, Graham; Trmcic, Jelena; Okazoe, Takashi Organic Process Research and Development, 2008 , vol. 12, # 2 p. 339 - 344

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.86
  • LogP   1.50988
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Fluoro-5-formylbenzonitrile sigma3-Fluoro-5-formylbenzonitrile manufacturer3-Fluoro-5-formylbenzonitrile price3-Fluoro-5-formylbenzonitrile structure3-Fluoro-5-formylbenzonitrile SDSbuy 3-Fluoro-5-formylbenzonitrile3-Fluoro-5-formylbenzonitrile supplier3-Fluoro-5-formylbenzonitrile uses3-Fluoro-5-formylbenzonitrile molecular weightprice of 3-Fluoro-5-formylbenzonitrile3-Fluoro-5-formylbenzonitrile chemical name formula of 3-Fluoro-5-formylbenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label