Lot numbers can be found on the outside label of a product:
2-Amino-5-bromo-4-methyl-3-nitropyridine
-
CAS No. 100367-40-6
- Cat. No. CS-M1656
- Purity≥96%
- MDL No.MFCD00092197
*For research and further manufacturing use only, not for direct human use.
Structure of 100367-40-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 100367-40-6
- Cat. No. CS-M1656
- Purity ≥96%
- MDL No. MFCD00092197
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₆BrN₃O₂
- Molecular Weight 232.03
- Synonym(s) 5-bromo-4-methyl-3-nitropyridin-2-amine
- SMILES CC1=C([N+]([O-])=O)C(N)=NC=C1Br
Description
2-Amino-5-bromo-4-methyl-3-nitropyridine features a fused pyridine core bearing strategically positioned amino, bromo, methyl, and nitro substituents. This electron-deficient heterocycle enables direct functionalization in cross-coupling and cyclization reactions. The ortho-nitro group enhances reactivity toward nucleophilic substitution, while the amino handle supports derivatization. Bench-stable under standard conditions, it serves as a key intermediate for bioactive molecule synthesis.
Application
2-Amino-5-bromo-4-methyl-3-nitropyridine serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via cross-coupling and reduction strategies. Its complementary functional groups—bromine for Pd-catalyzed coupling, nitro for selective reduction, and amino/methyl groups for derivatization—offer high synthetic flexibility. Bench-stable and compatible with standard purification methods, it facilitates rapid prototyping in medicinal chemistry and materials science applications.
Synthesis
-
Route1
-
In-stock
6635-86-5 - ~96%
-
In-stock
100367-40-6
References
-
Liu, Wansheng; Patel, Sunil S.; Cuniere, Nicolas; Lear, Yvonne; Deshpande, Prashant P.; Simon, Jeffrey N.; Lai, Chiajen; Pullockaran, Annie J.; Soundararajan, Nachimuthu; Bien, Jeffrey T. Patent: US2007/32503 A1, 2007 ; Location in patent: Page/Page column 8-9; 10 ;
-
-
Route2
-
In-stock
98198-48-2 - ~%
-
In-stock
100367-40-6
References
-
Journal of the American Chemical Society, , vol. 79, p. 6421,6423,6424
-
-
Route3
-
In-stock
695-34-1 - ~%
-
In-stock
100367-40-6
References
-
Journal of the American Chemical Society, , vol. 79, p. 6421,6423,6424
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 82.05
- LogP 1.64292
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Amino-5-bromo-4-methyl-3-nitropyridine sigma2-Amino-5-bromo-4-methyl-3-nitropyridine manufacturer2-Amino-5-bromo-4-methyl-3-nitropyridine price2-Amino-5-bromo-4-methyl-3-nitropyridine structure2-Amino-5-bromo-4-methyl-3-nitropyridine SDSbuy 2-Amino-5-bromo-4-methyl-3-nitropyridine2-Amino-5-bromo-4-methyl-3-nitropyridine supplier2-Amino-5-bromo-4-methyl-3-nitropyridine uses2-Amino-5-bromo-4-methyl-3-nitropyridine molecular weightprice of 2-Amino-5-bromo-4-methyl-3-nitropyridine2-Amino-5-bromo-4-methyl-3-nitropyridine chemical name formula of 2-Amino-5-bromo-4-methyl-3-nitropyridine