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CS-W001157 4
Total: USD 88.00

1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

  • CAS No. 100361-18-0

  • Cat. No. CS-W003524
  • Purity≥98%
  • MDL No.MFCD08458865

*For research and further manufacturing use only, not for direct human use.

1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid|CS-W003524

Structure of 100361-18-0

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General Information

  • CAS No. 100361-18-0
  • Cat. No. CS-W003524
  • Purity ≥98%
  • MDL No. MFCD08458865
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈ClFN₂O₃
  • Molecular Weight None
  • Synonym(s) 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
  • SMILES ClC1=C(F)C=C(C2=N1)C(C(C(O)=O)=CN2C3CC3)=O

Synthesis

  • Route1
    • Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate|CS-0046189
      96568-07-9
    • ~76%
    • In-stock
      1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid|CS-W003524
      100361-18-0

    References

    • Karoli, Tomislav; Mamidyala, Sreeman K.; Zuegg, Johannes; Fry, Scott R.; Tee, Ernest H.L.; Bradford, Tanya A.; Madala, Praveen K.; Huang, Johnny X.; Ramu, Soumya; Butler, Mark S.; Cooper, Matthew A. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2428 - 2433
  • Route2
    • null|null
      99735-42-9
    • ~%
    • In-stock
      1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid|CS-W003524
      100361-18-0

    References

    • US5281612 A1, ;
  • Route3
    • null|null
      99735-36-1
    • ~%
    • null|null
      99735-37-2
    • In-stock
      1-Cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid|CS-W003524
      100361-18-0

    References

    • US4571396 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.19
  • LogP   2.2221
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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