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Structure of 100348-93-4
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(R)-8a-methyl-3,4,8,8a-tetrahydronaphthalene-1,6(2H,7H)-dione is a stereodefined cyclic diketone featuring a rigid fused ring system with a methyl group at the 8a-position. This configuration imparts enhanced stereochemical stability and facilitates selective functionalization in asymmetric synthesis. The molecule serves as a valuable chiral synthon for natural product derivatization and complex molecular scaffolding.
(R)-8a-methyl-3,4,8,8a-tetrahydronaphthalene-1,6(2H,7H)-dione serves as a stereochemically defined bicyclic diketone scaffold for the synthesis of complex natural product analogs and pharmaceutical intermediates. Its rigid fused ring system enables predictable regioselective transformations, while the methyl group at C8a enhances metabolic stability in downstream applications. The compound exhibits excellent bench stability and facilitates efficient functionalization via standard carbonyl chemistry, including enolization, reduction, and nucleophilic addition, making it a practical building block in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: