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Structure of 1003298-73-4
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2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile features a boronate ester group flanked by two fluorine atoms and a nitrile at the para position, enabling efficient cross-coupling reactions. This bench-stable reagent integrates seamlessly into Suzuki-Miyaura protocols, delivering high functional group tolerance and predictable regioselectivity in complex molecule synthesis.
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The difluorophenyl moiety enhances metabolic stability and modulates electronic properties, while the tetramethylboronate group offers excellent bench stability, mild reaction conditions, and broad functional group tolerance. This compound facilitates efficient construction of biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: