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CS-W001157 4
Total: USD 88.00

2-(Bromomethyl)-6-fluoropyridine

  • CAS No. 100202-78-6

  • Cat. No. CS-W006122
  • Purity≥95%
  • MDL No.MFCD09953532
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(Bromomethyl)-6-fluoropyridine|CS-W006122

Structure of 100202-78-6

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Description

2-(Bromomethyl)-6-fluoropyridine features a reactive bromomethyl group flanked by a fluorinated pyridine ring, enabling efficient coupling in cross-coupling and nucleophilic substitution reactions. The electron-deficient aromatic system enhances electrophilicity, while the bench-stable nature facilitates handling under standard conditions.

Application

2-(Bromomethyl)-6-fluoropyridine serves as a versatile synthetic building block for constructing fluorinated heterocycles and pharmaceutical intermediates. The bromomethyl group enables efficient nucleophilic substitution reactions, while the ortho-fluorine facilitates directed metalation or palladium-catalyzed coupling processes. Its bench-stable nature and compatibility with diverse functional groups make it ideal for multi-step synthesis in medicinal chemistry and process development workflows.

General Information

  • CAS No. 100202-78-6
  • Cat. No. CS-W006122
  • Purity ≥95%
  • MDL No. MFCD09953532
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrFN
  • Molecular Weight 190.01
  • Synonym(s) 6-(bromomethyl)-2-fluoropyridine
  • SMILES FC1=CC=CC(CBr)=N1

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.1156
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group :
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

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