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CS-W001157 4
Total: USD 88.00

8-Aminooctanoic acid

  • CAS No. 1002-57-9

  • Cat. No. CS-W019464
  • Purity≥97%
  • MDL No.MFCD00008245

*For research and further manufacturing use only, not for direct human use.

8-Aminooctanoic acid|CS-W019464

Structure of 1002-57-9

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General Information

  • CAS No. 1002-57-9
  • Cat. No. CS-W019464
  • Purity ≥97%
  • MDL No. MFCD00008245
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₂
  • Molecular Weight 159.23
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCN

Description

8-Aminooctanoic acid is a linear aliphatic amino acid featuring an amine group at the terminal position, enabling straightforward conjugation and functionalization. This structure supports applications in peptide synthesis, polymer chemistry, and bioconjugation where long spacer arms or tailored solubility are required.

Application

8-Aminooctanoic acid serves as a versatile bifunctional building block for synthesizing peptide analogs, bioactive lactams, and polymer precursors. Its aliphatic chain provides favorable solubility and stability, while the terminal amine and carboxylic acid groups enable efficient coupling reactions under standard conditions. The molecule functions effectively in solid-phase synthesis and facilitates the construction of cyclic scaffolds via intramolecular amidation, offering reliable access to structurally defined intermediates for medicinal chemistry and materials applications.

Synthesis

  • Route1
    • Methyl 8-aminooctanoate|CS-0865444
      59080-49-8
    • ~97%
    • In-stock
      8-Aminooctanoic acid|CS-W019464
      1002-57-9

    References

    • Texaco Inc. Patent: US3933873 A1, 1976 ;
  • Route2

    References

    • Bell, R. A.; Faggiani, R.; Hunter, H. N.; Lock, C. J. L. Canadian Journal of Chemistry, 1992 , vol. 70, p. 186 - 196
  • Route3
    • In-stock
      8-Bromooctanoic acid|CS-W007700
      17696-11-6
    • ~%
    • In-stock
      8-Aminooctanoic acid|CS-W019464
      1002-57-9
    • null|null
      21573-31-9

    References

    • US4510331 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.3703
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   7

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