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CS-W001157 4
Total: USD 88.00

1,4-Dibromo-2,3-dichlorobenzene

  • CAS No. 100191-20-6

  • Cat. No. CS-0157210
  • Purity≥97%
  • MDL No.MFCD09878188

*For research and further manufacturing use only, not for direct human use.

1,4-Dibromo-2,3-dichlorobenzene|CS-0157210

Structure of 100191-20-6

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General Information

  • CAS No. 100191-20-6
  • Cat. No. CS-0157210
  • Purity ≥97%
  • MDL No. MFCD09878188
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Br₂Cl₂
  • Molecular Weight 304.79
  • Synonym(s) None
  • SMILES C1=CC(=C(C(=C1Br)Cl)Cl)Br

Description

1,4-Dibromo-2,3-dichlorobenzene features a highly halogenated aromatic core with complementary bromo and chloro substituents positioned for orthogonal reactivity. This electron-deficient scaffold enables selective cross-coupling in transition-metal-catalyzed transformations, offering robust stability under standard conditions. The molecule's defined substitution pattern facilitates precise incorporation into complex molecular architectures.

Application

1,4-Dibromo-2,3-dichlorobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of complex polycyclic architectures through palladium-catalyzed reactions. Its orthogonal halogen reactivity profile facilitates sequential functionalization, while the stability of its aryl halide moieties supports reliable handling and purification. This compound functions effectively in Suzuki, Stille, and Negishi coupling protocols, offering predictable regioselectivity for the synthesis of biaryl scaffolds relevant to pharmaceutical and materials research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.5184
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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