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Structure of 1001754-59-1
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This protected fluorinated pyrrolidine derivative features a tert-butoxycarbonyl group that enhances stability and solubility in organic media. The fluorine substituent imparts strong electron-withdrawing character, enabling precise modulation of reactivity in peptide synthesis. Its bench-stable, moisture-tolerant profile simplifies handling during solid-phase and solution-phase applications.
1-(tert-Butoxycarbonyl)-3-fluoropyrrolidine-3-carboxylic acid serves as a stable, bench-ready building block for the synthesis of fluorinated pyrrolidine-containing compounds. The Boc group enables straightforward protection and orthogonal deprotection, while the C3-fluorine imparts enhanced metabolic stability and modulates conformational preferences. It functions effectively in standard amide coupling, reduction, and cyclization protocols, facilitating access to bioactive scaffolds relevant to medicinal chemistry and peptide-based drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: