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*For research and further manufacturing use only, not for direct human use.
Structure of 1001353-87-2
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This chiral pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and two methyl groups at the 4-position, enhancing steric shielding. The carboxylic acid functionality enables direct coupling in peptide synthesis, while the (S)-configuration ensures stereochemical fidelity in complex molecule assembly. Bench-stable under standard conditions, it integrates seamlessly into solid-phase and solution-phase workflows.
(S)-1-(tert-butoxycarbonyl)-4,4-dimethylpyrrolidine-2-carboxylic acid serves as a robust chiral building block for the synthesis of bioactive heterocycles and peptide mimetics. The tert-butyl ester group enables straightforward deprotection under mild acidic conditions, while the sterically hindered 4,4-dimethyl substitution enhances conformational rigidity and metabolic stability. Its well-defined stereochemistry and functional group tolerance facilitate integration into standard coupling protocols and diversification strategies in medicinal chemistry workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: