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tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate

  • CAS No. 1000933-99-2

  • Cat. No. CS-0029835
  • Purity≥95%
  • MDL No.MFCD09702342

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate|CS-0029835

Structure of 1000933-99-2

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General Information

  • CAS No. 1000933-99-2
  • Cat. No. CS-0029835
  • Purity ≥95%
  • MDL No. MFCD09702342
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₃
  • Molecular Weight 227.30
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1CC2(CC(O)C2)C1

Description

tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate features a rigid spirocyclic scaffold that enhances conformational stability, while the pendant hydroxyl group enables selective derivatization. This bench-stable carbamate serves as a protected amine handle in complex molecule synthesis.

Application

tert-Butyl (6-hydroxyspiro[3.3]heptan-2-yl)carbamate serves as a stable, bench-ready chiral auxiliary for asymmetric synthesis, enabling controlled functionalization at the C6 position of the spirocyclic framework. The protected hydroxyl group exhibits high tolerance to standard organic transformations, while the carbamate moiety facilitates selective deprotection and conjugation. This scaffold functions effectively in the construction of complex polycyclic systems and offers predictable stereochemical outcomes in iterative synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.8146
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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