1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene

Name: 1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1000578-25-5
Cat. No. CS-0101728
Purity≥98%
MDL No.MFCD09878148

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene|CS-0101728

Structure of 1000578-25-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1000578-25-5
Cat. No. CS-0101728
Purity ≥98%
MDL No. MFCD09878148
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₁Br₂Cl
Molecular Weight 326.46
Synonym(s) 4-Chloro-3,5-dibromo-tert-butylbenzene
SMILES CC(C1=CC(Br)=C(Cl)C(Br)=C1)(C)C

Description

1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene features a sterically hindered aromatic core with complementary halogenation patterns enabling selective cross-coupling. The tert-butyl group enhances solubility and stability under standard conditions, while the bromo and chloro substituents offer orthogonal reactivity for sequential functionalization in synthetic sequences.

Application

1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling the construction of complex aryl architectures with high regiocontrol. The tert-butyl group provides steric bulk and enhanced stability, while the strategically positioned bromo and chloro substituents offer orthogonal reactivity for sequential functionalization. This compound facilitates efficient access to substituted biaryls and heterocyclic scaffolds under standard coupling conditions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 0
LogP 5.1625
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1000578-25-5 sigma1000578-25-5 manufacturer1000578-25-5 price1000578-25-5 structure1000578-25-5 SDSbuy 1000578-25-51000578-25-5 supplier1000578-25-5 uses1000578-25-5 molecular weightprice of 1000578-25-51000578-25-5 chemical name formula of 1000578-25-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1,3-Dibromo-5-(tert-butyl)-2-chlorobenzene

CAS No. 1000578-25-5

Recommended Products