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CS-W001157 4
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3-Iodo-4-methoxy-1H-pyrrolo[3,2-c]pyridine

  • CAS No. 1000341-25-2

  • Cat. No. CS-0041234
  • Purity≥96%
  • MDL No.MFCD09749970

*For research and further manufacturing use only, not for direct human use.

3-Iodo-4-methoxy-1H-pyrrolo[3,2-c]pyridine|CS-0041234

Structure of 1000341-25-2

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General Information

  • CAS No. 1000341-25-2
  • Cat. No. CS-0041234
  • Purity ≥96%
  • MDL No. MFCD09749970
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇IN₂O
  • Molecular Weight 274.06
  • Synonym(s) 3-IODO-4-METHOXY-5-AZAINDOLE
  • SMILES COC1=NC=CC2=C1C(I)=CN2

Description

3-Iodo-4-methoxy-1H-pyrrolo[3,2-c]pyridine features a fused bicyclic core with iodine and methoxy substituents positioned for orthogonal reactivity. This electron-deficient heterocycle integrates readily into cross-coupling protocols, enabling efficient access to complex scaffolds in medicinal chemistry and materials science.

Application

3-Iodo-4-methoxy-1H-pyrrolo[3,2-c]pyridine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. The iodide group enables efficient palladium-catalyzed cross-coupling reactions, while the methoxy substituent offers moderate electronic modulation and enhanced solubility. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.91
  • LogP   2.1761
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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