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CS-W001157 4
Total: USD 88.00

2-(4-Nitrophenyl)ethanol

  • CAS No. 100-27-6

  • Cat. No. CS-M0671
  • Purity≥97%
  • MDL No.MFCD00010202

*For research and further manufacturing use only, not for direct human use.

2-(4-Nitrophenyl)ethanol|CS-M0671

Structure of 100-27-6

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General Information

  • CAS No. 100-27-6
  • Cat. No. CS-M0671
  • Purity ≥97%
  • MDL No. MFCD00010202
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) p-nitrophenethyl alcohol
  • SMILES OCCC1=CC=C([N+]([O-])=O)C=C1

Description

2-(4-Nitrophenyl)ethanol features a para-nitro aromatic ring linked to a hydroxyethyl side chain, enabling facile functionalization in synthetic routes. This bench-stable compound integrates readily into conjugate addition and coupling reactions, serving as a key intermediate for bioactive molecule synthesis.

Synthesis

  • Route1
    • 4-Nitrobenzeneacetic acid Indobufen  Impurity|CS-0229459
      104-03-0
    • ~76%
    • In-stock
      2-(4-Nitrophenyl)ethanol|CS-M0671
      100-27-6

    References

    • Sakai, Norio; Kawana, Keita; Ikeda, Reiko; Nakaike, Yumi; Konakahara, Takeo European Journal of Organic Chemistry, 2011 , # 17 p. 3178 - 3183
  • Route2
    • Ethyl 2-(4-nitrophenyl)acetate|CS-W005171
      5445-26-1
    • ~77%
    • In-stock
      2-(4-Nitrophenyl)ethanol|CS-M0671
      100-27-6

    References

    • Jagdale, Arun R.; Paraskar, Abhimanyu S.; Sudalai, Arumugam Synthesis, 2009 , # 4 p. 660 - 664
  • Route3

    References

    • Nikitin, Oleg M.; Magdesieva, Tatiana V. Mendeleev Communications, 2011 , vol. 21, # 4 p. 194 - 195

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.37
  • LogP   1.1296
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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