10K Golden Scaffold Library
| Cat. No. : CS-L927 |
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| （9,968） |
| Library Contents: |
| Designed to maximize efficiency in hit discovery and optimization, this compound library is built on a foundation of diverse Bemis-Murcko scaffolds, with each scaffold is represented by two specifically derived molecules. This strategy ensures broad chemical space through scaffold diversity while enabling preliminary functional group exploration. This approach provides early structure-activity relationship (SAR) insights for every scaffold, making it a valuable tool for accelerating drug discovery. |
| Size (Pre-dissolved DMSO or Solid) | Stock | Price |
|---|---|---|
| In-stock | Get quote |
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Description & Advantages
Composition
| Formulation: | A 10k compound library, which balances both excellent diversity and the capacity for preliminary analysis of structure-activity relationships, making it an ideal starting library for high-throughput screening. |
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| Container: | 96- or 384-well Plates with Peelable Foil Seals; 96-well Format Sample Storage Tubes with Screw Caps and Optional 2D Barcodes. |
| Storage: | -80°C |
| Shipping: | Blue ice or dry ice |
• A unique collection of 10,000 compounds with 5,000 Bemis-Murcko scaffolds, making it a valuable tool for accelerating drug discovery.
• Scaffold Diversity: The library contains a wide array of distinct chemical scaffolds, ensuring broad coverage of chemical space and maximizing the probability of identifying hit molecules.
• Functional Group Richness: For each scaffold, two derivative molecules are designed, introducing functional groups with varying properties, sizes, and polarities at different sites to enable preliminary exploration of structure-activity relationships.
• All compounds are available off the shelf.
• All compounds are validated by LCMS or NMR to ensure high purity and quality.
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