Natural Product-like Compound Library
| Cat. No. : CS-L905 |
|---|
| （4,825） |
| Library Contents: |
| Natural products are an attractive source with varied structures that exhibit potent biological activities, and desirable pharmacological profiles. The core scaffold of a natural product can also provide a biologically validated framework upon which to display diverse functional groups. Inspired by bioactive natural products, natural product-like compounds, occupying the same chemical space, are ideally suited to explore and to facilitate understanding of biological pathways. ChemScene 5K Natural Product-like Compound Library consists of 4,825 natural product-like compounds. Each compound has scaffold of natural products or Tanimoto coefficient >0.6 with natural products. The natural-likeness scoring of these compounds is >-2. What’s more, compounds in the library are drug-like and readily available for re-supply, making it a powerful tool for new drug research and development. It can be widely applied in high-throughput screening (HTS) and high-content screening (HCS). |
| Size (Pre-dissolved DMSO or Solid) | Stock | Price |
|---|---|---|
| In-stock | Get quote |
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Description & Advantages
Composition
| Formulation: | A collection of 4,825 compounds supplied as pre-dissolved DMSO solutions. |
|---|---|
| Container: | 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode. |
| Storage: | -80°C |
| Shipping: | Blue ice or dry ice |
• A unique collection of natural product-like compound library.
• Each molecule contains scaffold of natural products or has a Tanimoto similarity coefficient greater than 0.6 with 40K natural products, and natural-likeness scoring is more than -2.
• Compatible with “Lipinski” s Rule of Five”, with multiple characteristics such as calculated good permeability (-3.2 • Passed all associated MedChem filters, particularly pan assay interference compound (PAINS) motifs, to remove any inappropriate chemical structures and avoid false hits. • All compounds are available off the shelf. Pre-plates of 10 mM DMSO solutions, convenient to use. • NMR and HPLC validated to ensure high purity and quality.
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