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Home   >>   Product   >>  MEK
Cat.No. Product Name / Introduction Added
CS-0058 CI-1040 August 2016
CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM, 100-fold more selective for MEK1/2 than MEK5.
 
CS-0059 Selumetinib August 2016
Selumetinib (AZD6244; ARRY-142886) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc.
 
CS-0060 Trametinib August 2016
Trametinib (GSK1120212; JTP 74057) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.
 
CS-0061 Trametinib_(DMSO_solvate) August 2016
Trametinib (GSK1120212; JTP 74057) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.
 
CS-0062 PD0325901 August 2016
PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with IC50 of 0.
 
CS-0169 PD98059 August 2016
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2.
 
CS-0173 U0126 August 2016
U0126-EtOH(U-0126) is a highly selective inhibitor of MEK1/2 with IC50 of 0.
 
CS-0198 AS703026 August 2016
AS703026(Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines.
 
CS-0214 BIX02188 August 2016
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.
 
CS-0215 BIX02189 August 2016
BIX02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM.
 
CS-0217 AZD8330 August 2016
AZD8330(ARRY-424704; ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM.
 
CS-0222 PD318088 August 2016
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
 
CS-0521 Cobimetinib August 2016
Cobimetinib(GDC-0973; XL518) is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).
 
CS-0627 MEK162 August 2016
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
 
CS-0846 MEK_inhibitor August 2016
MEK inhibitor is a potent MEK inhibitor, antitumor agent.
 
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CS-0494 XAV-939
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CS-0592 YM-201636
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CS-0608 BMS-754807
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CS-0627 MEK162
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CS-0765 CYT387 (sulfate salt)
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CS-1956 XL413
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CS-B0575 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methyl-
CS-B0576 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 4-amino-, 1,1-dimethylethyl ester
CS-B0577 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-(phenylmethyl)-

 
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