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Home   »   Product Pathways  »  Glucocorticoid Receptor  »  Meprednisone

Products are for research use only. Not for human use. We do not sell to patients.


CS-2222 Meprednisone


Structure Price and Availability of    Meprednisone
United States
Size Price Stock
10mg $96 In-stock Inquiry
100mg $768 In-stock
200 mg Get quote
500 mg Get quote
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Meprednisone  M.Wt:  372.45
Meprednisone  Formula: C22H28O5
Meprednisone  Solubility: DMSO 77 mg/mL; Water <1 mg/mL
Meprednisone  Purity: >98%
Meprednisone  Storage:  Please store the product under the recommended conditions in the Certificate of Analysis.
CAS: 1247-42-3

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Meprednisone is a glucocorticoid and a methylated derivative of prednisone. Target: Glucocorticoid Receptor Meprednisone is a glucocorticoid and a methylated derivative of prednisone. The methylprednisone to MPL area under the curve ratio decreased from 0.19 +/- 0.04 in control to 0.14 +/- 0.03 in ketoconazole-treated rats (P less than .05) due to altered interconversion between these steroids. An improved pharmacokinetic/dynamic receptor/gene-mediated model characterized the steroid receptor binding and induction of tyrosine aminotransferase activity after i.v. MPL sodium succinate (10 mg/kg). In contrast to previous in vitro studies, ketoconazole at maximally tolerated doses failed to antagonize the steroid receptor-mediated activity of MPL [1].

Glucocorticoid Receptor  |  
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