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Home   »   Product Pathways  »  γ-secretase  »  DAPT

Products are for research use only. Not for human use. We do not sell to patients.


CS-0264 DAPT


(GSI-IX;GSI IX)
Structure Price and Availability of    DAPT
United States
Size Price Stock
5mg $56 In-stock Inquiry
10mg $96 In-stock
50mg $296 In-stock
100 mg Get quote
200 mg Get quote
 Distributor In Japan:  フナコシ株式会社 www.funakoshi.co.jp    電話番号:81-3-5684-1620   
 FAX番号:81-3-5684-1775
Inquiry for price and availability only. Please place your order via our email or fax.
Contact us for competitive discounts on bulk quantities .
  • Data Sheet
  • Introduction
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DAPT  M.Wt:  432.46
DAPT  Formula: C23H26F2N2O4
DAPT  Solubility: 10 mM in DMSO
DAPT  Purity: >98%
DAPT  Storage:  Please store the product under the recommended conditions in the Certificate of Analysis.
CAS: 208255-80-5

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DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo. IC50 value: Target: γ-secretase Does not effect APPα and APPβ levels. DAPT blocks Notch signaling in hybrid human-mouse fetal thymus organ culture (FTOC). Activity causes neural cells to commit to neuronal differentiation.

γ-secretase  |  
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CHEMSCENE, LLC
Tel: 732-484-9848
Fax: 888-484-5008
Email:  [email protected]
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Products are for research use only. Not for human use. We do not sell to patients. Sitemap | Inhibitor © Copyright 2012. All Rights Reserved.