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Home   »   Product Pathways  »  Others  »  AX20017

Products are for research use only. Not for human use. We do not sell to patients.


CS-6196 AX20017


(AX-20017;AX 20017)
Structure Price and Availability of    AX20017
United States
Size Price Stock
5mg $70 In-stock Inquiry
10mg $100 In-stock
25mg $210 In-stock
50mg $360 In-stock
100 mg Get quote
200 mg Get quote
 Distributor In Japan:  フナコシ株式会社 www.funakoshi.co.jp    電話番号:81-3-5684-1620   
 FAX番号:81-3-5684-1775
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AX20017  M.Wt:  264.34
AX20017  Formula: C13H16N2O2S
AX20017  Solubility: DMSO: ≥ 32 mg/mL
AX20017  Purity: >98%
AX20017  Storage:  Please store the product under the recommended conditions in the Certificate of Analysis.
CAS: 329221-38-7

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AX20017 is a small-molecule protein kinase G PknG inhibitor with an IC50 of 0.39 μM. IC50&Target: 0.39 μM (PknG)[1] InVitro: The compound AX20017 inhibitor is bound deep within a narrow pocket formed by the inter lobe cleft of the PknG domain. The main chain Glu233:O and Val235:NH of PknG form hydrogen bonds with AX20017[2].AX20017 results in mycobacterial transfer to lysosomes and killing of the mycobacteria. AX20017 does not affect the human kinases, whereas the activity of PknG is effectively inhibited. AX20017 did not affect cellular morphology, membrane ruffling, or macropinocytosis[3].

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Products are for research use only. Not for human use. We do not sell to patients. Sitemap | Inhibitor © Copyright 2012. All Rights Reserved.