Tianeptine

Tianeptine
Cat. No. : CS-0433 CAS No. : 72797-41-2
M. Wt. : 436.9522
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Name: Tianeptine; 
Cat. No. : CS-0433
CAS No. : 72797-41-2
Formula: C21H25ClN2O4S
M. Wt. : 436.9522
Solubility: DMSO: ≥ 4.5 mg/mL

Activity:

Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. IC50 Value: N/A Target: 5-HT Receptor Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.

Protocol:

References:

Broqua P; Baudrie V; Chaouloff F Differential effects of the novel antidepressant tianeptine on L-5-hydroxytryptophan (5-HTP)-elicited corticosterone release and body weight loss. Eur Neuropsychopharmacol. 1992 Jun;2(2):115-20.

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