Solutol HS-15
CAS No. : 61909-81-7

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  • Data Sheet

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Name: Solutol HS-15; 
Cat. No. : CS-0040442
CAS No. : 61909-81-7
Formula: N/A
M. Wt. :
Solubility: DMSO

Activity:

Solutol HS-15 is a permeability enhancer and also a weak inhibitor of cytochrome P450 3A (CYP3A) with an IC50 of 5 μM. IC50 & Target: CYP3A[1]

Protocol:

References:

Shubber S, et al. Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures. Pharm Res. 2015 Feb;32(2):516-27.

Bittner B, et al. Impact of Solutol HS 15 on the pharmacokinetic behavior of midazolam upon intravenous administration to male Wistar rats. Eur J Pharm Biopharm. 2003 Jul;56(1):143-6.

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