SR-4370
CAS No. : 1816294-67-3

SR-4370
Cat. No. : CS-0040447
M. Wt. : 304.33
Size Stock Price Quantity Add to Cart Quotation Online
5mg In-stock $140.0
10mg In-stock $240.0
50mg In-stock $750.0
100mg In-stock $1200.0
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  • Data Sheet

  • Introduction

  • SDS

  • COA & Spectra

Name: SR-4370; 
Cat. No. : CS-0040447
CAS No. : 1816294-67-3
Formula: C17H18F2N2O
M. Wt. : 304.33
Solubility: DMSO: ≥ 150 mg/mL

Activity:

SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. IC50 & Target: IC50: 0.13 μM (HDAC1), 0.58 μM (HDAC2), 0.006 μM (HDAC3), 2.3 μM (HDAC8), 3.4 μM (HDAC6)[1] In Vitro: SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. SR-4370 is cytotoxic to the breast cancer cells (MDA-MB-231), with an IC50 of 12.6 μM[1].

Protocol:

References:

LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.

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