Sabutoclax
CAS No. : 1228108-65-3

Sabutoclax
Cat. No. : CS-0003805
M. Wt. : 700.78
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  • Data Sheet

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Name: Sabutoclax; BI-97C1
Cat. No. : CS-0003805
CAS No. : 1228108-65-3
Formula: C42H40N2O8
M. Wt. : 700.78
Solubility: DMSO

Activity:

Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively. IC50 & Target: IC50: 0.32 μM (Bcl-2), 0.31 μM (Bcl-XL), 0.20 μM (Mcl-1), and 0.62 μM (Bfl-1) [1].

Protocol:

References:

Wei J , et al. BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. J Med Chem. 2010 May 27; 53(10):4166-76.

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