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Cat.No. Product Name / Introduction Added
CS-6233 Isosilybin February 2017
Isosilybin (Isosilybinin) is a flavonoid from milk thistle; inhibits CYP3A4 induction with an IC50 of 74 μM.
 
CS-6235 Columbin February 2017
Columbina is a diterpenoid furanolactone with anti-inflammation activity.
 
CS-6234 Proguanil February 2017
Proguanil is an antimalarial prodrug that is metabolized to the active metabolite cycloguanil, a dihydrofolate reductase (DHFR) inhibitor.
 
CS-6238 Hyaluronic-acid February 2017
Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications.
 
CS-6239 PAC-14028 February 2017
PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist.
 
CS-6236 Ecteinascidin-770 February 2017
Ecteinascidin 770 (ET-770) is a 1,2,3,4-tetrahydroisoquinoline alkaloid with potent anti-cancer activities; inhibits U373MG cells with an IC50 of 4.
 
CS-6232 SH5-07 February 2017
SH5-07 is a hydroxamic acid based Stat3 inhibitor with an IC50 of 3.
 
CS-6237 MELK-8a-hydrochloride February 2017
MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
 
CS-6231 R121919 February 2017
R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
 
CS-6228 Chitosan February 2017
Chitosan is a natural polycationic linear polysaccharide derived from chitin.
 
CS-6224 Octenidine-dihydrochloride February 2017
Octenidine dihydrochloride is an effective antiseptic compound for skin mucous membranes and wounds.
 
CS-6230 Dovitinib-lactate February 2017
Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM.
 
CS-6227 MRT68921 February 2017
MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.
 
CS-6221 Myricetin February 2017
Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
 
CS-6229 CCT196969 February 2017
CCT196969, a pan-RAF inhibitor, inhibits BRAF with an IC50 of 0.
 
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CS-0645 Rimonabant
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.
CS-2222 Meprednisone
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
CS-0264 DAPT
DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo.
CS-0613 Tideglusib
Tideglusib(NP-031112) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM.
CS-0757 SB-705498
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.
CS-0766 Aripiprazole
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.
CS-1971 Haloperidol
Haloperidol blocks dopamine receptors in in the treatment of schizophrenia, acute psychosis, and delirium.
CS-0609 SCH 527123
SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
CS-0361 Boceprevir
Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CS-0625 Avosentan
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
CS-0494 XAV-939
XAV939 is a small molecule and selective Wnt pathway β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively.
CS-0592 YM-201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
CS-0608 BMS-754807
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.
CS-0627 MEK162
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
CS-0765 CYT387 (sulfate salt)
CYT387 sulfate(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
CS-1955 CC-401
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
CS-1956 XL413
XL413 is a potent and selective Cdc7 inhibitor with an IC50 of 3.
CS-B0575 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methyl-
CS-B0576 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 4-amino-, 1,1-dimethylethyl ester
CS-B0577 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-(phenylmethyl)-

 
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