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Cat.No. Product Name / Introduction Added
CS-5768 SIS3 August 2016
SIS3 is a potent and selective inhibitor of Smad3.
 
CS-5769 Terlipressin August 2016
Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells.
 
CS-5774 TBHQ August 2016
TBHQ is a phenolic antioxidant, a selective inducer of Nrf2 in a preclinical model of ICH.
 
CS-5742 Argipressin August 2016
Argipressin is a Antidiuretic hormone that has been found in most mammalian species.
 
CS-5747 Nafarelin August 2016
Nafarelin is a gonadotropin-releasing hormone (GnRH) agonists that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
 
CS-5743 Cyclic-somatostatin August 2016
Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers.
 
CS-5692 Pulchinenoside-A August 2016
Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.
 
CS-5693 Pulchinenoside-C August 2016
Anemoside B4 is Pulsatilla koreana Nakai that have many numerous biological effects in vitro, including enhancing hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.
 
CS-5691 Hederacoside-C August 2016
Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.
 
CS-1899 NBI-98782 August 2016
NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.
 
CS-5397 Echinocystic-acid August 2016
Echinocystic acid a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties.
 
CS-5754 FPTQ August 2016
FPTQ is mGluR1 antagonist with IC50 of 6 nM and 1.
 
CS-5757 CFMTI August 2016
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist with IC50 of 2.
 
CS-5753 IMR-1 August 2016
IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μmol/L.
 
CS-5752 IMR-1A August 2016
IMR-1A is the metabolite of IMR-1.
 
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CS-0645 Rimonabant
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.
CS-2222 Meprednisone
Meprednisone is a glucocorticoid and a methylated derivative of prednisone.
CS-0264 DAPT
DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo.
CS-0613 Tideglusib
Tideglusib(NP-031112) is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM.
CS-0757 SB-705498
SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.
CS-0766 Aripiprazole
Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.
CS-1971 Haloperidol
Haloperidol blocks dopamine receptors in in the treatment of schizophrenia, acute psychosis, and delirium.
CS-0609 SCH 527123
SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.
CS-0361 Boceprevir
Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CS-0625 Avosentan
Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
CS-0494 XAV-939
XAV939 is a small molecule and selective Wnt pathway β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and 4 nM for the inhibition of TNKS1 and TNKS2, respectively.
CS-0592 YM-201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
CS-0608 BMS-754807
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.
CS-0627 MEK162
MEK162(ARRY-438162; ARRY-162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM.
CS-0765 CYT387 (sulfate salt)
CYT387 sulfate(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
CS-1955 CC-401
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
CS-1956 XL413
XL413 is a potent and selective Cdc7 inhibitor with an IC50 of 3.
CS-B0575 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-methyl-
CS-B0576 1H-Pyrrolo[2,3-b]pyridine-1-carboxylic acid, 4-amino-, 1,1-dimethylethyl ester
CS-B0577 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-(phenylmethyl)-

 
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